WebCircHIPK2 has been found remarkably upregulated in nasopharyngeal carcinoma (NPC) tissues . In vitro and in vivo studies in animal models showed that circHIPK2 promotes proliferation of NPC cells while knockdown of circHIPK2 dampens the growth of NPC cells . Mechanistically, circHIPK2 downregulated HIPK2 at the protein levels and consequently ... WebIn contrast, patients with high circHIPK2 expression had lower overall survival rate and disease-free survival rate than those with low circHIPK2 expression. circHIPK2 expression in normal intestinal epithelial cells was lower than that in CRC cell lines. circHIPK2 promoted CRC progression. miR-485-5p reduced CRC progression. miR-485-5p, as the ...

circHIPK2-mediated σ-1R promotes endoplasmic …

WebAug 22, 2024 · Transplantation of the NLRP3 KO gut microbiota inhibited the increased expression of circHIPK2 in CUS mice. a–e The correlation of the relative abundances of phyla (Bacteroidetes and Firmicutes ... WebResults circHIPK2 (hsa-circ-0001756) is considerably upregulated in NPC. Differentially expressed circRNAs were explored via RNA sequencing data in four NPC along with normal nasopharyngeal tissues to determine their significance in the onset and progress of the disease (unpublished data) ().The results showed elevated contents of circRNAs were … the phoenix cups framework

Ubiquitylomeic Responses to Streptococcus agalactiae in BMEC JIR

WebJan 15, 2024 · CircHIPK2 increased SIGMAR1 expression by suppressing miR-124-2HG activity . In bladder cancer, circHIPK3 affected the expression of heparanase by competitively binding to miR-558 [ 23 ]; circRNA MYLK and lncRNA H19 increase the expression of DNMT3, VEGFA, and ITGB1 by suppressing miR-29a-3P activity [ 24 ]. WebMay 8, 2024 · A pLC5-circHipk2-Flag vector and pLC5-circHipk2vector were constructed by Geenseed Biotech (Guangzhou, China). Cellular lysates from C2C12 myoblasts with a transfecting pLC5-circHipk2-Flag vector or pLC5-circHipk2 were divided into an input group and pull-down group, in which the pull-down group was used for circHipk2 pull … Web(circHIPK2) and depression and the observation that the level of circHIPK2 expression was significantly increased in CUS-treated mice compared with that in the control group, further experiments were performed. FMT significantly ameliorated astrocyte dysfunction in recipient mice treated with CUS via inhibition of circHIPK2 expression. the phoenix davenport