WebYou hereby acknowledge your responsibility during the COVID-19 pandemic for educating yourself on CDC and local health guidance for mitigating your exposure to the COVID-19 virus. WebPyruvate kinase deficiency (PKDef) is an inherited hemolytic anemia caused by a defect in the enzyme pyruvate kinase. Loss of function of this enzyme results in premature death of red blood cells. Affected dogs do not have sufficient quantities of red blood cells to adequately supply the body with oxygen. Observable signs in affected dogs may ...
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