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WebSm is 1 of 4 autoantigens commonly referred to as extractable nuclear antigens (ENA). The other ENA are RNP, SS-A/Ro, and SS-B/La. Each ENA is composed of 1 or more proteins associated with small nuclear RNA species (snRNA) ranging in size from 80 to approximately 350 nucleotides. Antibodies to ENA are common in patients with … WebJul 14, 2011 · Structure of the LSm657 Complex: An Assembly Intermediate of the LSm1 7 and LSm2 8 Rings. Structure of the LSm657 Complex: An Assembly Intermediate of the LSm1 7 and LSm2 8 Rings ... The nuclear LSm2-8 (like Sm) complex and the cytoplasmic LSm1-7 complex play a central role in mRNA splicing and degradation, respectively. The … WebThe SMN complex: an assembly machine for RNPs In eukaryotic cells, the biogenesis of spliceosomal small nuclear ribonucleoproteins (snRNPs) and likely other RNPs is mediated by an assemblyosome, the survival of motor neurons (SMN) complex. The SMN complex, composed of SMN and the Gemins (2-7), binds to the Sm proteins and to snRNAs and … greenhouseservice