Webb19 juli 2024 · Integration of KLF4 ChIP-seq and our RNA sequencing data by binding and expression target analysis ( Wang et al., 2013 ) showed significant activation of transcriptional function in TEADi KCs ( Supplementary Figure S2 a). Predicted KLF4-activated genes were enriched for differentiation gene ontology terms ( Supplementary … Webb6 apr. 2024 · The transcriptional coactivators YAP1/TAZ and the family of transcription factors TEAD1-4 are the downstream effectors of the Hippo pathway and regulate …
CSA: a web service for the complete process of ChIP-Seq analysis
WebbThe applicant will combine cell and molecular biology state-of-the-art techniques such as ChIP-seq, RNA-seq, single-cell RNA-seq, ATAC-seq, CLIP-seq and other epigenomic and epitranscriptomic analyzes. Embryonic stem cells, and several differentiation models will be used to study how epigenetic and epitranscriptomic marks regulate pluripotency. WebbChromatin immunoprecipitation followed by sequencing (ChIP-seq) is a technique for genome-wide profiling of DNA-binding proteins, histone modifications or nucleosomes. … オトコエシ
EWS-FLI1 perturbs MRTFB/YAP-1/TEAD target gene regulation …
WebbThe Tead family transcription factors are the major intracellular mediators of the Hippo-Yap pathway. Despite the importance of Hippo signaling in tumorigenesis, Tead-dependent downstream... WebbNUAK2 is a direct target of YAP. a Heatmap representing TEAD4/H3K27ac ChIP-seq signal in a window of ±3 Kb from the center of TEAD4 peaks. Clustering results from the K … Webb13 apr. 2024 · Our goal is to describe the use of Bioconductor software to perform some basic tasks in the analysis of ChIP-Seq data. We will use several functions in the as-yet-unreleased chipseq package, which provides convenient interfaces to other powerful packages such as ShortRead and IRanges. We will also use the lattice and rtracklayer … parasta lapsille leirit