T.pyriformis toxicity

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Spletaquatic toxicity and abiotic thiol reactivity of se-lectedamides.Thespeciﬁcaimswere:(1)todeter-mine reactive toxicants by examining the effects on Tetrahymena pyriformis population growth of short-term exposure to representatives of each structural group; (2) to determine the toxic po-tency for larger … SpletDescription In this endpoint, toxicity is determined when it affects a protozoa bacteria, T. Pyriformis. The concentration of compounds on T. Pyriformis are assessed in terms of …

Assessment of the potential toxicity of herbicides and their

Splet18. jul. 2006 · Toxicity of various compounds has been measured in many studies by their toxic effects against Tetrahymena pyriformis. Efforts have also been made to use … Splet01. mar. 2010 · A large toxicity data set containing the toxicities of 250 phenols and 252 aliphatic compounds to Tetrahymena pyriformis was classified into different groups … fis global payments

Screening Snake Venoms for Toxicity to Tetrahymena Pyriformis …

Splet01. mar. 2014 · Results: This study described the development of Quantitative Structure Toxicity Relationship (QSTR) model for the prediction of aqueous toxicity against T. … SpletThe toxicities to T. pyriformis of 514 possible non-polar narcotics were assessed. A QSAR to predict toxicity was created from a training set of 87 classic non-polar narcotics (the saturated alcohols and ketones): log IGC (50) (-1) = 0.78 log P-2.01 (n = 87, r (2) = 0.96). This model was then used to predict the toxicity of the remaining chemicals. Splet05. maj 2015 · National Center for Biotechnology Information campsites near sandringham

National Center for Biotechnology Information

Tetrahymena pyriformis: a tool for toxicological studies. A review

Splet01. mar. 2024 · Thresholds of excess toxicity have been evaluated by comparing with fish toxicity sensitivity. • Threshold of excess toxicity to T. pyriformis is different from fish, D. magna and V. fischeri. • The factors that influence toxicity ratio calculated from baseline level are discussed. Splet01. mar. 2011 · Tetrahymena pyriformis is an attractive test organism for the assessment of environmental impact of toxicants (Kahn et al., 2007). Several quantitative … campsites near sandbanks dorsetSpletThe cytotoxicity was assessed by four different cell viability assays (3- [4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide reduction (MTT), neutral red uptake (NRU), resazurin dye (AlamarBlue), 5-carboxyfluorescein diacetate acetoxymethyl ester (CFDA-AM)) for the HepG2 and by cell count and MTT for T. pyriformis. fis global ortigas

"SpletABSTRACT. Quantitative structure-activity relationship (QSAR) is important for safe, rapid and effective risk assessment of chemicals. In this study, two QSAR models were established with 1230 chemicals to predict toxicity towards Tetrahymena pyriformis using multiple linear regression (MLR) method. The topological(T)-QSAR model was developed … " - T.pyriformis toxicity

T.pyriformis toxicity

Tetrahymena pyriformis - an overview ScienceDirect Topics

Spletof T. pyriformis, which was used as a measure of the toxicity of the compounds. The experi-mental acute toxicity values of the nitrobenzenes to T. pyriformis are listed in Table I, as well as the corresponding names, molecular formulas and CAS numbers. The bigger the value of –log IGC50, the higher is the acute toxicity of the compound. Splet08. apr. 2005 · This paper presents a mechanistic analysis of aquatic toxicity data, quantified as pIGC50 assessed in the 40 h Tetrahymena pyriformis population growth impairment assay, for 40 polyhydroxybenzene derivatives. The toxicity trends of these phenolic compounds have been shown to be consistent with mechanistic organic …

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Splet02. nov. 2024 · In silico toxicity prediction of the selected four compounds has been performed using pkCSM-pharmacokinetics web-based server. The server has identified … Splet06. apr. 2024 · One detoxification mechanism is the intracellular bioaccumulation of toxic metals, which has been observed in various ciliate species 14, 15, 21, 22, 23, 24, 25. Bioaccumulation is usually...

SpletSnake venom has been shown to have an antiparasitic effect. The venom from the cobra Naja sumatrana showed antiprotozoan activity towards the ciliate Tetrahymena … SpletBackground: Many QSAR studies have been developed to predict acute toxicity over several biomarkers like Pimephales promelas, Daphnia magna and Tetrahymena pyriformis. Regardless of the progress made in this field there are still some gaps to be resolved such as the prediction of aquatic toxicity over the protozoan T. pyriformis still lack a QSAR …

SpletToxicity assays involved the Microtox test, the T. pyriformis population growth impairment test employing three different processes (flasks, tubes, microplates), and the T. … SpletTOXICITY OF NITROBENZENES TO T. pyriformis 1113 cular structures. For this purpose, a group of 45 nitrobenzene compounds having the structure of a single nitrobenzene ring …

Spletzoa Tetrahymena pyriformis with regard to the acute toxicity of antidepressants. The cyto-toxic effects of a range of currently marketed antidepressants were evaluated using the MTT assay, and the IC50 values were determined for each. These IC50 values did not corre-late with the FTI (Fatal Toxicity Index) values in humans.

Splet15. maj 2024 · The cytotoxins from several cobra species were tested and manifested toxicity for infusorians. Light microscopy revealed that, because of the cytotoxin action, … campsites near sandringham norfolkSplet12. feb. 2007 · Alachlor exerted a toxic effect on the two nontarget cells used. The results for diuron and its photo and biotransformation products indicated that most of the … fis global orlando flSplet01. jun. 2024 · The estimation of toxicity of aromatic compounds toward Tetrahymena pyriform ( T. pyriformis) is an important ecologic and pharmaceutical task. T. pyriformis … fis global orlando campus addressSplet12. apr. 2024 · The importance of conceptual density functional theory (DFT)-based global descriptors on portraying the chemical reactivity and biological activity, including toxicity prediction of molecules, has been demonstrated in detail [1,2,3,4,5,6,7,8,9,10].Electrophilicity-based charge transfer (ECT) is one such descriptor … campsites near royal welsh showgroundSplet12. feb. 2007 · Toxicity assays involved the Microtox® test, the T. pyriformis population growth impairment test employing three different processes (flasks, tubes, microplates), and the T. pyriformis nonspecific … campsites near sanford ncSplet01. mar. 2024 · The toxicity ratio (TR), a descriptor of excess toxicity, was calculated as follows: (1) TR = T pred baseline / T obs (2) log TR = log 1 / T obs − log 1 / T pred … campsites near rowardennanSplet06. apr. 2024 · (a–f) T. pyriformis is treated with 0.5 mM GdCl 3 in 1% PPY medium. ... Zhang, T. et al. Acute toxicity of heavy metals to tetrahymena in an in vitro experiment … fis global pictures