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Tripartite motif containing 46

WebSep 1, 2024 · TRIM46 is a member of the family of tripartite motif (TRIM)-containing proteins that serve as important regulators of tumorigenesis. Here we investigate the possible role … WebMar 1, 2024 · TRIM46 is a RING finger E3 ligase which belongs to TRIM (tripartite motif-containing) protein family. TRIM46 is required for neuronal polarity and axon specification by driving the formation of parallel microtubule arrays, whereas its embryological functions remain to be determined yet.

Tripartite motif family - Wikipedia

WebPubMed WebNov 22, 2024 · Results: Tripartite motif containing 46 was highly expressed in ccRCC, and its upregulation revealed an unfavorable prognosis. A nomogram based on TRIM46 expressions and other independent prognostic factors could robustly predict the overall survival of tumor patients. books to make your mind stronger https://reflexone.net

Tripartite Motif-Containing 46 Promotes Viability and …

WebOct 14, 2008 · Tripartite motif-containing protein 54 Alternative names Muscle-specific RING finger protein ( MuRF) Muscle-specific RING finger protein 3 ( MuRF-3; MuRF3) RING finger protein 30 Gene names Name TRIM54 Synonyms MURF, MURF3, RNF30 Organism names Organism Homo sapiens (Human) Taxonomic identifier 9606 NCBI Taxonomic … WebAug 25, 2024 · Tripartite motif-containing family proteins play significant roles in various physiological or pathological conditions by acting as ubiquitin E3 ligases, such as cell proliferation and development, DNA damage and repair, neurodegenerative disease, innate immune response, and carcinogenesis ( Nisole et al., 2005; Ozato et al., 2008; … WebNov 2, 2010 · Recently we described an intracellular cytosolic protein called tripartite motif-containing 21 (TRIM21) that is capable of binding to an invariant region of antibody molecules via its PRYSPRY domain ( 4 ). We found this activity to be structurally, thermodynamically, and kinetically conserved across mammals ( 5 ). harworth business park

Antibodies mediate intracellular immunity through tripartite motif ...

Category:Tripartite motif family - Wikipedia

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Tripartite motif containing 46

Tripartite motif-containing 3 (TRIM3) enhances ER signaling

Webtripartite motif-containing protein 46, geneY, tripartite, fibronectin type III and C-terminal SPRY motif-containing GeneRIFs: Gene References Into Functions Axonal TAU Sorting Requires the C-terminus of TAU but is Independent of … WebNov 3, 2024 · The tripartite motif family (TRIM) of proteins have been intensively studied in virus infection. One member, TRIM46, could regulate cancer cell viability, apoptosis, and …

Tripartite motif containing 46

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WebAug 1, 2008 · The tripartite motif is always present at the N-terminus of the TRIM proteins. The order of the domains that compose the motif is also conserved: a RING finger domain precedes the B-box motif (s), and a Coiled-coil (CC) region invariably follows. Even if one of the domains is missing, the order of the remaining ones is maintained. WebJan 1, 2024 · The constitutive androstane receptor (CAR) is a nuclear receptor that acts as a transcription factor for a variety of genes, including genes encoding xenobiotic, steroid, and drug-metabolizing enzymes and transporters. Transactivation of a target gene by a transcription factor is generally mediated through the concerted and stepwise recruitment …

WebMar 30, 2024 · Jiang W, Cai X, Xu T, Liu K, Yang D, Fan L, et al. Tripartite motif-containing 46 promotes viability and inhibits apoptosis of osteosarcoma cells by activating NF-B signaling through ... WebE3 ubiquitin ligase tripartite motif-containing 71 promotes the proliferation of non-small cell lung cancer through the inhibitor of kappaB-α/nuclear factor kappaB pathway. ONCOTARGET. 2024 Jul 7;9(13):10880-10890. ... 46. Cai L, Li J, Zhao J, Guo Y, Xie M, Zhang X, Wang L, Tian H, Li A, Li Q, Miao Y.

WebSep 10, 2024 · Tripartite motif-containing (TRIM) proteins are a new class of SUMO E3 ligases, which regulate the SUMOylation of proteins. However, the precise molecular mechanism and function of TRIM3 in... WebNov 3, 2024 · Avian influenza A H7N9 emerged in 2013, threatening public health and causing acute respiratory distress syndrome, and even death, in the human population. However, the underlying mechanism by which H7N9 virus causes human infection remains elusive. Herein, we infected A549 cells with H7N9 virus for different times and assessed …

WebMar 15, 2024 · Total RNA was isolated from cells and tissues using the TRIzol Reagent (Invitrogen) according to the manufacturer's protocol, and reverse-transcribed into complementary DNA using relevant kits (Toyobo). circ_0007429, tripartite motif containing 71 (TRIM71), and miRNA expression were examined using UltraSYBR Mixture (CWbio) on …

Web目前,临床上已有不少研究报道指出,三基序蛋白29(tripartite motif-containing 29,TRIM29)、三基序蛋白59(tripartite motif-containing 59,TRIM59)在胃癌、乳腺癌以及卵巢癌等多种恶性肿瘤中存在异常表达,可能参与肿瘤的发生、发展过程 ,但其与NSCLC的关系尚且处于探究阶段 ... books to movies 2020WebWei C, Cheng J, Zhou B, et al. Tripartite motif containing 28 (TRIM28) promotes breast cancer metastasis by stabilizing TWIST1 protein. Sci Rep . 2016;6:29822. doi:10.1038/srep29822 harworth church of england academyWebMar 31, 2024 · Correlatively, tripartite motif containing-21 (TRIM21), an interferon-inducible E3 ligase, may function as a negative regulator of Nrf2 signaling in pressure-overloaded hearts. ... [21,46,47,48]. This section discusses new findings regarding the regulatory effects of cardiac metabolic alterations on cardiac oxidative stress and their potential ... harworth cemeteryWebNov 22, 2024 · Results: Tripartite motif containing 46 was highly expressed in ccRCC, and its upregulation revealed an unfavorable prognosis. A nomogram based on TRIM46 … harworth coalvilleWebTRIM46, tripartite motif containing 46 Vertebrate Orthologs 4 Human Diseases less References 1 with disease annotations Mutations, Alleles, and Phenotypes less … harworth church of englandharworth classic car showWebTripartite motif-containing protein 21, also known as E3 ubiquitin-protein ligase TRIM21, is a protein that in humans is encoded by the TRIM21 gene. [5] [6] Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. It is expressed in most human tissues. harworth church of england school